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Transcriptomic analysis of mouse EL4 T cells upon T cell activation and in response to protein synthesis inhibition via cycloheximide treatment

T cell activation involves the recognition of a foreign antigen complexed to the major histocompatibility complex on the antigen presenting T cell to the T cell receptor. This leads to activation of signaling pathways, which ultimately leads to induction of key cytokine genes responsible for eradica...

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Detalles Bibliográficos
Autores principales: Lim, Pek Siew, Hardy, Kristine, Peng, Kaiman, Shannon, Frances M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778634/
https://www.ncbi.nlm.nih.gov/pubmed/26981393
http://dx.doi.org/10.1016/j.gdata.2015.12.009