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Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer

Prostate cancer (PCa) is the second most common cancer in men. The Androgen Receptor (AR) is the major driver of PCa and the main target of therapy in the advanced setting. AR is a nuclear receptor that binds the chromatin and regulates transcription of genes involved in cancer cell proliferation an...

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Detalles Bibliográficos
Autores principales: Nevedomskaya, Ekaterina, Stelloo, Suzan, van der Poel, Henk G., de Jong, Jeroen, Wessels, Lodewyk F.A., Bergman, Andries M., Zwart, Wilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778643/
https://www.ncbi.nlm.nih.gov/pubmed/26981385
http://dx.doi.org/10.1016/j.gdata.2015.12.020