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Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer
Prostate cancer (PCa) is the second most common cancer in men. The Androgen Receptor (AR) is the major driver of PCa and the main target of therapy in the advanced setting. AR is a nuclear receptor that binds the chromatin and regulates transcription of genes involved in cancer cell proliferation an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778643/ https://www.ncbi.nlm.nih.gov/pubmed/26981385 http://dx.doi.org/10.1016/j.gdata.2015.12.020 |