Cargando…

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer

Prostate cancer (PCa) is the second most common cancer in men. The Androgen Receptor (AR) is the major driver of PCa and the main target of therapy in the advanced setting. AR is a nuclear receptor that binds the chromatin and regulates transcription of genes involved in cancer cell proliferation an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nevedomskaya, Ekaterina, Stelloo, Suzan, van der Poel, Henk G., de Jong, Jeroen, Wessels, Lodewyk F.A., Bergman, Andries M., Zwart, Wilbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Data in Brief
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778643/ https://www.ncbi.nlm.nih.gov/pubmed/26981385 http://dx.doi.org/10.1016/j.gdata.2015.12.020

Ejemplares similares

Androgen receptor profiling predicts prostate cancer outcome
por: Stelloo, Suzan, et al.
Publicado: (2015)

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors
por: Nevedomskaya, Ekaterina, et al.
Publicado: (2014)

Loss of androgen receptor signaling in prostate cancer‐associated fibroblasts (CAFs) promotes CCL2‐ and CXCL8‐mediated cancer cell migration
por: Cioni, Bianca, et al.
Publicado: (2018)

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors
por: Singh, Abhishek A, et al.
Publicado: (2018)

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma
por: Stelloo, Suzan, et al.
Publicado: (2016)

Integrative epigenetic taxonomy of primary prostate cancer
por: Stelloo, Suzan, et al.
Publicado: (2018)

TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth
por: Palit, Sander AL, et al.
Publicado: (2019)

Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
por: Severson, Tesa, et al.
Publicado: (2022)

Enzalutamide therapy for advanced prostate cancer: efficacy, resistance and beyond
por: Linder, Simon, et al.
Publicado: (2018)

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics
por: Siefert, Joseph C., et al.
Publicado: (2021)

Functional mapping of androgen receptor enhancer activity
por: Huang, Chia-Chi Flora, et al.
Publicado: (2021)

Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
por: Cioni, Bianca, et al.
Publicado: (2020)

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
por: Kneppers, Jeroen, et al.
Publicado: (2022)

Genome-wide chromatin accessibility, DNA methylation and gene expression analysis of histone deacetylase inhibition in triple-negative breast cancer
por: Bustos, Matias A., et al.
Publicado: (2017)

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases
por: Severson, Tesa M., et al.
Publicado: (2021)

The Effects of Enzalutamide Monotherapy on Multiparametric 3T MR Imaging in Prostate Cancer
por: Van der Roest, Rosanne CV., et al.
Publicado: (2016)

Radium-223 Treatment of Patients with Metastatic Castration Resistant Prostate Cancer: Biomarkers for Stratification and Response Evaluation
por: van der Zande, Kim, et al.
Publicado: (2021)

Nucleosomal chromatin in the mature sperm of Drosophila melanogaster
por: Elnfati, Abdul Hakim, et al.
Publicado: (2015)

Current Routine Testosterone Immunoassays Are Unsuitable for Lowering the General Castration Cutoff Recommendation to <0.7 nmol/l (20 ng/dl)
por: van Rossum, Huub H., et al.
Publicado: (2023)

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer
por: Long, Mark D., et al.
Publicado: (2021)

Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model
por: Passier, Margot, et al.
Publicado: (2023)

Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models
por: Sugawara, Tatsuo, et al.
Publicado: (2019)

Identification of Tox chromatin binding properties and downstream targets by DamID-Seq
por: de Jesus Domingues, António Miguel, et al.
Publicado: (2016)

An ATAC-seq atlas of chromatin accessibility in mouse tissues
por: Liu, Chuanyu, et al.
Publicado: (2019)

Chromatin accessibility and transcriptome landscapes of Monomorium pharaonis brain
por: Wang, Mingyue, et al.
Publicado: (2020)

Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo
por: Kim, Yongsoo, et al.
Publicado: (2019)

Genome-wide identification of accessible chromatin regions in bumblebee by ATAC-seq
por: Zhao, Xiaomeng, et al.
Publicado: (2020)

Genome-wide mapping of the distribution of CarD, RNAP σ(A), and RNAP β on the Mycobacterium smegmatis chromosome using chromatin immunoprecipitation sequencing
por: Landick, Robert, et al.
Publicado: (2014)

A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer
por: Palit, Sander A. L., et al.
Publicado: (2021)

An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development
por: Koh, Pang Wei, et al.
Publicado: (2016)

Transcriptome and chromatin accessibility in porcine intestinal epithelial cells upon Zearalenone exposure
por: Wang, Haifei, et al.
Publicado: (2019)

Genome-wide chromatin accessibility and gene expression profiling during flatfish metamorphosis
por: Guerrero-Peña, Laura, et al.
Publicado: (2023)

A scATAC-seq atlas of chromatin accessibility in axolotl brain regions
por: Feng, Weimin, et al.
Publicado: (2023)

From Omics to Multi-Omics Approaches for In-Depth Analysis of the Molecular Mechanisms of Prostate Cancer
por: Nevedomskaya, Ekaterina, et al.
Publicado: (2022)

Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation
por: Baumgart, Simon J., et al.
Publicado: (2020)

Analyzing alternative splicing data of splice junction arrays from Parkinson patients' leukocytes before and after deep brain stimulation as compared with control donors
por: Soreq, Lilach, et al.
Publicado: (2015)

ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes
por: Galhardo, Mafalda, et al.
Publicado: (2014)

Dysregulated Transcriptional Control in Prostate Cancer
por: Baumgart, Simon J., et al.
Publicado: (2019)

Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation
por: Severson, Tesa M., et al.
Publicado: (2016)

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells
por: Launonen, Kaisa-Mari, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8ek5h77eommmcthbdvhvapmv9e