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MIF inhibition reverts the gene expression profile of human melanoma cell line-induced MDSCs to normal monocytes

Myeloid-derived suppressor cells (MDSCs) are potently immunosuppressive innate immune cells that accumulate in advanced cancer patients and actively inhibit anti-tumor T lymphocyte responses [1]. Increased numbers of circulating MDSCs directly correlate with melanoma patient morbidity and reduced an...

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Detalles Bibliográficos
Autores principales: Waigel, Sabine, Rendon, Beatriz E., Lamont, Gwyneth, Richie, Jamaal, Mitchell, Robert A., Yaddanapudi, Kavitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778657/
https://www.ncbi.nlm.nih.gov/pubmed/26981417
http://dx.doi.org/10.1016/j.gdata.2015.12.025