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MIF inhibition reverts the gene expression profile of human melanoma cell line-induced MDSCs to normal monocytes
Myeloid-derived suppressor cells (MDSCs) are potently immunosuppressive innate immune cells that accumulate in advanced cancer patients and actively inhibit anti-tumor T lymphocyte responses [1]. Increased numbers of circulating MDSCs directly correlate with melanoma patient morbidity and reduced an...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778657/ https://www.ncbi.nlm.nih.gov/pubmed/26981417 http://dx.doi.org/10.1016/j.gdata.2015.12.025 |