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Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway

The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3). We identified small molecule compounds that activ...

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Detalles Bibliográficos
Autores principales: Green, R.R., Wilkins, C., Pattabhi, S., Dong, R., Loo, Y., Gale, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778670/
https://www.ncbi.nlm.nih.gov/pubmed/26981429
http://dx.doi.org/10.1016/j.gdata.2016.01.020