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Transcriptional analysis of antiviral small molecule therapeutics as agonists of the RLR pathway
The recognition of pathogen associated molecular patterns (PAMPs) by pattern recognition receptors (PRR) during viral infection initiates the induction of antiviral signaling pathways, including activation of the Interferon Regulator Factor 3 (IRF3). We identified small molecule compounds that activ...
Autores principales: | Green, R.R., Wilkins, C., Pattabhi, S., Dong, R., Loo, Y., Gale, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778670/ https://www.ncbi.nlm.nih.gov/pubmed/26981429 http://dx.doi.org/10.1016/j.gdata.2016.01.020 |
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