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Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells
The adenomatous polyposis coli (APC) tumour suppressor gene is mutated in about 80% of colorectal cancers (CRC) Brannon et al. (2014) [1]. APC is a large multifunctional protein that regulates many biological functions including Wnt signalling (through the regulation of beta-catenin stability) Reya...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778681/ https://www.ncbi.nlm.nih.gov/pubmed/26981430 http://dx.doi.org/10.1016/j.gdata.2016.02.001 |