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Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells

The adenomatous polyposis coli (APC) tumour suppressor gene is mutated in about 80% of colorectal cancers (CRC) Brannon et al. (2014) [1]. APC is a large multifunctional protein that regulates many biological functions including Wnt signalling (through the regulation of beta-catenin stability) Reya...

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Detalles Bibliográficos
Autores principales: King, Lauren E., Love, Christopher G., Sieber, Oliver M., Faux, Maree C., Burgess, Antony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778681/
https://www.ncbi.nlm.nih.gov/pubmed/26981430
http://dx.doi.org/10.1016/j.gdata.2016.02.001