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Analysis of telomerase target gene expression effects from murine models in patient cohorts by homology translation and random survival forest modeling
Acute myeloid leukemia (AML) is an aggressive and rapidly fatal blood cancer that affects patients of any age group. Despite an initial response to standard chemotherapy, most patients relapse and this relapse is mediated by leukemia stem cell (LSC) populations. We identified a functional requiremen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778749/ https://www.ncbi.nlm.nih.gov/pubmed/26981425 http://dx.doi.org/10.1016/j.gdata.2016.01.014 |