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The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) and several neurodegenerative disorders known as tauopathies are characterized by misfolding and aggregation of tau protein. Although several studies have suggested the potential of traditional Chinese medicine (TCM) as treatment for neurodegenerative diseases, t...

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Detalles Bibliográficos
Autores principales: Chang, Kuo-Hsuan, Chen, I-Cheng, Lin, Hsuan-Yuan, Chen, Hsuan-Chiang, Lin, Chih-Hsin, Lin, Te-Hsien, Weng, Yu-Ting, Chao, Chih-Ying, Wu, Yih-Ru, Lin, Jung-Yaw, Lee-Chen, Guey-Jen, Chen, Chiung-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778784/
https://www.ncbi.nlm.nih.gov/pubmed/27013866
http://dx.doi.org/10.2147/DDDT.S96454