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The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) and several neurodegenerative disorders known as tauopathies are characterized by misfolding and aggregation of tau protein. Although several studies have suggested the potential of traditional Chinese medicine (TCM) as treatment for neurodegenerative diseases, t...
Autores principales: | Chang, Kuo-Hsuan, Chen, I-Cheng, Lin, Hsuan-Yuan, Chen, Hsuan-Chiang, Lin, Chih-Hsin, Lin, Te-Hsien, Weng, Yu-Ting, Chao, Chih-Ying, Wu, Yih-Ru, Lin, Jung-Yaw, Lee-Chen, Guey-Jen, Chen, Chiung-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778784/ https://www.ncbi.nlm.nih.gov/pubmed/27013866 http://dx.doi.org/10.2147/DDDT.S96454 |
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