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Clinical utility of nivolumab in the treatment of advanced melanoma

Melanomas are highly immunogenic tumors that evade the immune system by exploiting innate checkpoint pathways, rendering effector T-cells anergic. The immunotherapeutic approach of checkpoint inhibition can restore and invigorate endogenous antitumor T-cell responses and has become an important trea...

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Detalles Bibliográficos
Autores principales: Asmar, Ramsey, Yang, Jessica, Carvajal, Richard D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778791/
https://www.ncbi.nlm.nih.gov/pubmed/27013881
http://dx.doi.org/10.2147/TCRM.S78039