Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD)

Facioscapulohumeral muscular dystrophy (FSHD) is typically an adult onset dominant myopathy. Epigenetic changes in the chromosome 4q35 region linked to both forms of FSHD lead to a relaxation of repression and increased somatic expression of DUX4-fl (DUX4-full length), the pathogenic alternative spl...

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Detalles Bibliográficos
Autores principales: Jones, Takako I., Parilla, Megan, Jones, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778869/
https://www.ncbi.nlm.nih.gov/pubmed/26942723
http://dx.doi.org/10.1371/journal.pone.0150938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778869/
https://www.ncbi.nlm.nih.gov/pubmed/26942723
http://dx.doi.org/10.1371/journal.pone.0150938

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