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The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein

Fatal Ebola virus infection is characterized by a systemic inflammatory response similar to septic shock. Ebola glycoprotein (GP) is involved in this process through activating dendritic cells (DCs) and macrophages. However, the mechanism is unclear. Here, we showed that LSECtin (also known as CLEC4...

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Detalles Bibliográficos
Autores principales: Zhao, Dianyuan, Han, Xintao, Zheng, Xuexing, Wang, Hualei, Yang, Zaopeng, Liu, Di, Han, Ke, Liu, Jing, Wang, Xiaowen, Yang, Wenting, Dong, Qingyang, Yang, Songtao, Xia, Xianzhu, Tang, Li, He, Fuchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778874/
https://www.ncbi.nlm.nih.gov/pubmed/26943817
http://dx.doi.org/10.1371/journal.ppat.1005487