Cargando…

The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein

Fatal Ebola virus infection is characterized by a systemic inflammatory response similar to septic shock. Ebola glycoprotein (GP) is involved in this process through activating dendritic cells (DCs) and macrophages. However, the mechanism is unclear. Here, we showed that LSECtin (also known as CLEC4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Dianyuan, Han, Xintao, Zheng, Xuexing, Wang, Hualei, Yang, Zaopeng, Liu, Di, Han, Ke, Liu, Jing, Wang, Xiaowen, Yang, Wenting, Dong, Qingyang, Yang, Songtao, Xia, Xianzhu, Tang, Li, He, Fuchu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778874/ https://www.ncbi.nlm.nih.gov/pubmed/26943817 http://dx.doi.org/10.1371/journal.ppat.1005487

Ejemplares similares

Correction: The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein
por: Zhao, Dianyuan, et al.
Publicado: (2016)

Involvement of LSECtin in the hepatic natural killer cell response
por: Yang, Juntao, et al.
Publicado: (2016)

Liver Sinusoidal Endothelial Cell Lectin, LSECtin, Negatively Regulates Hepatic T-Cell Immune Response
por: Tang, Li, et al.
Publicado: (2009)

Activation of mTORC1 by LSECtin in macrophages directs intestinal repair in inflammatory bowel disease
por: Li, Qian, et al.
Publicado: (2020)

Mouse LSECtin as a model for a human Ebola virus receptor
por: Pipirou, Zoi, et al.
Publicado: (2011)

LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus
por: Gramberg, Thomas, et al.
Publicado: (2005)

C-type lectin LSECtin interacts with DC-SIGNR and is involved in hepatitis C virus binding
por: Li, Yi, et al.
Publicado: (2009)

Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs
por: Qi, Yinglin, et al.
Publicado: (2015)

Chimeric Rabies Virus-Like Particles Containing Membrane-Anchored GM-CSF Enhances the Immune Response against Rabies Virus
por: Kang, Hongtao, et al.
Publicado: (2015)

Generation of Recombinant Rabies Virus CVS-11 Expressing eGFP Applied to the Rapid Virus Neutralization Test
por: Xue, Xianghong, et al.
Publicado: (2014)

Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice
por: Gai, Weiwei, et al.
Publicado: (2017)

DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice
por: Chi, Hang, et al.
Publicado: (2017)

Equine-Origin Immunoglobulin Fragments Protect Nonhuman Primates from Ebola Virus Disease
por: Wang, Hualei, et al.
Publicado: (2019)

Immunogenicity Assessment of Rift Valley Fever Virus Virus-Like Particles in BALB/c Mice
por: Li, Yuetao, et al.
Publicado: (2020)

Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis
por: Zhang, Yinan, et al.
Publicado: (2022)

Porcine epidemic diarrhea virus virus-like particles produced in insect cells induce specific immune responses in mice
por: Wang, Cuiling, et al.
Publicado: (2017)

A rabies virus-vectored vaccine expressing two copies of the Marburg virus glycoprotein gene induced neutralizing antibodies against Marburg virus in humanized mice
por: Bi, Jinhao, et al.
Publicado: (2022)

Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition by LSECtin
por: Bertuzzi, Sara, et al.
Publicado: (2022)

Packaging of Rift Valley fever virus pseudoviruses and establishment of a neutralization assay method
por: Li, Yuetao, et al.
Publicado: (2018)

A rapid immunochromatographic test strip for detecting rabies virus antibody
por: Wang, Hualei, et al.
Publicado: (2010)

Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection
por: Zheng, Xuexing, et al.
Publicado: (2016)

Tat Peptide-Mediated Soluble Expression of the Membrane Protein LSECtin-CRD in Escherichia coli
por: Dong, Guofu, et al.
Publicado: (2013)

Debating DAP12
por: Van Epps, Heather L.
Publicado: (2005)

CXCL8 Up-Regulated LSECtin through AKT Signal and Correlates with the Immune Microenvironment Modulation in Colon Cancer
por: Fang, Shaojun, et al.
Publicado: (2022)

MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular imminity in rhesus macaques
por: Wang, Chong, et al.
Publicado: (2016)

Clinical significance of LSECtin and its association with PVR in non-small-cell lung cancer patients
por: Zhang, Yizhong, et al.
Publicado: (2020)

Intracerebral Administration of Recombinant Rabies Virus Expressing GM-CSF Prevents the Development of Rabies after Infection with Street Virus
por: Wang, Hualei, et al.
Publicado: (2011)

Recombinant Antibodies to the Ebola Virus Glycoprotein
por: Panina, A. A., et al.
Publicado: (2017)

615. Daptomycin (DAP) Synergy with β-Lactams in DAP-Resistant (DAP-R) E. faecium (Efm) Is Dependent On PBP5 Sequence and β-Lactam-binding Affinity
por: Khan, Ayesha, et al.
Publicado: (2019)

Dap10 and Dap12 Form Distinct, but Functionally Cooperative, Receptor Complexes in Natural Killer Cells
por: Wu, Jun, et al.
Publicado: (2000)

Distinct usage of three C-type lectins by Japanese encephalitis virus: DC-SIGN, DC-SIGNR, and LSECtin
por: Shimojima, Masayuki, et al.
Publicado: (2014)

Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein
por: Yi, Dongrong, et al.
Publicado: (2022)

Isatis indigotica root polysaccharides as adjuvants for an inactivated rabies virus vaccine
por: Zhang, Weijiao, et al.
Publicado: (2016)

Genomic Pathways Associated with Daptomycin (DAP) Resistance in DAP-Susceptible Enterococcus faecium Harboring Substitutions in LiaFSR
por: Tran, Truc T, et al.
Publicado: (2017)

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
por: Zhao, Yuguang, et al.
Publicado: (2016)

ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection
por: Zhao, Dianyuan, et al.
Publicado: (2022)

Novel chimeric virus-like particles vaccine displaying MERS-CoV receptor-binding domain induce specific humoral and cellular immune response in mice
por: Wang, Chong, et al.
Publicado: (2017)

Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding
por: Gramberg, Thomas, et al.
Publicado: (2008)

A Novel Bacterium-Like Particle-Based Vaccine Displaying the SUDV Glycoprotein Induces Potent Humoral and Cellular Immune Responses in Mice
por: Xu, Shengnan, et al.
Publicado: (2019)

Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair
por: Yang, Wenting, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_docudjf9sep57hjus7l31mjdig