Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels

Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, we have investigated the role of residues at this i...

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Detalles Bibliográficos
Autores principales: Bertozzi, Carlo, Zimmermann, Iwan, Engeler, Sibylle, Hilf, Ricarda J. C., Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778918/
https://www.ncbi.nlm.nih.gov/pubmed/26943937
http://dx.doi.org/10.1371/journal.pbio.1002393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778918/
https://www.ncbi.nlm.nih.gov/pubmed/26943937
http://dx.doi.org/10.1371/journal.pbio.1002393

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