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Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels
Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, we have investigated the role of residues at this i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778918/ https://www.ncbi.nlm.nih.gov/pubmed/26943937 http://dx.doi.org/10.1371/journal.pbio.1002393 |