Cargando…

Malignancy of Cancers and Synthetic Lethal Interactions Associated With Mutations of Cancer Driver Genes

The mutation status of cancer driver genes may correlate with different degrees of malignancy of cancers. The doubling time and multidrug resistance are 2 phenotypes that reflect the degree of malignancy of cancer cells. Because most of cancer driver genes are hard to target, identification of their...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaosheng, Zhang, Yue, Han, Ze-Guang, He, Kun-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778998/
https://www.ncbi.nlm.nih.gov/pubmed/26937901
http://dx.doi.org/10.1097/MD.0000000000002697