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Malignancy of Cancers and Synthetic Lethal Interactions Associated With Mutations of Cancer Driver Genes
The mutation status of cancer driver genes may correlate with different degrees of malignancy of cancers. The doubling time and multidrug resistance are 2 phenotypes that reflect the degree of malignancy of cancer cells. Because most of cancer driver genes are hard to target, identification of their...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778998/ https://www.ncbi.nlm.nih.gov/pubmed/26937901 http://dx.doi.org/10.1097/MD.0000000000002697 |