Deconvolution and IVIVC: Exploring the Role of Rate-Limiting Conditions

In vitro-in vivo correlations (IVIVCs) play an important role in formulation development and drug approval. At the heart of IVIVC is deconvolution, the method of deriving an in vivo “dissolution profile” for comparison with in vitro dissolution data. IVIVCs are generally believed to be possible for...

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Detalles Bibliográficos
Autores principales: Margolskee, Alison, Darwich, Adam S., Galetin, Aleksandra, Rostami-Hodjegan, Amin, Aarons, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779109/
https://www.ncbi.nlm.nih.gov/pubmed/26667356
http://dx.doi.org/10.1208/s12248-015-9849-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779109/
https://www.ncbi.nlm.nih.gov/pubmed/26667356
http://dx.doi.org/10.1208/s12248-015-9849-y

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