A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity

Drug-induced nephrotoxicity still hampers drug development, because current translation from in vitro or animal studies to human lacks high predictivity. Often, renal adverse effects are recognized only during clinical stages of drug development. The current study aimed to establish a robust and a m...

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Detalles Bibliográficos
Autores principales: Nieskens, Tom T. G., Peters, Janny G. P., Schreurs, Marieke J., Smits, Niels, Woestenenk, Rob, Jansen, Katja, van der Made, Thom K., Röring, Melanie, Hilgendorf, Constanze, Wilmer, Martijn J, Masereeuw, Rosalinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779111/
https://www.ncbi.nlm.nih.gov/pubmed/26821801
http://dx.doi.org/10.1208/s12248-016-9871-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779111/
https://www.ncbi.nlm.nih.gov/pubmed/26821801
http://dx.doi.org/10.1208/s12248-016-9871-8

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