PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus

AIMS/HYPOTHESIS: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the deteriorating glycaemic control associated with diabetes mellitus. The aims of t...

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Detalles Bibliográficos
Autores principales: Mellado-Gil, José Manuel, Jiménez-Moreno, Carmen María, Martin-Montalvo, Alejandro, Alvarez-Mercado, Ana Isabel, Fuente-Martin, Esther, Cobo-Vuilleumier, Nadia, Lorenzo, Petra Isabel, Bru-Tari, Eva, de Gracia Herrera-Gómez, Irene, López-Noriega, Livia, Pérez-Florido, Javier, Santoyo-López, Javier, Spyrantis, Andreas, Meda, Paolo, Boehm, Bernhard O., Quesada, Ivan, Gauthier, Benoit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779135/
https://www.ncbi.nlm.nih.gov/pubmed/26813254
http://dx.doi.org/10.1007/s00125-016-3864-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779135/
https://www.ncbi.nlm.nih.gov/pubmed/26813254
http://dx.doi.org/10.1007/s00125-016-3864-0

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