The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

Oncocytomas are predominantly benign neoplasms possessing pathogenic mitochondrial mutations and accumulation of respiration-defective mitochondria, characteristics of unknown significance. Using exome and transcriptome sequencing, we identified two main subtypes of renal oncocytoma. Type 1 is diplo...

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Detalles Bibliográficos
Autores principales: Joshi, Shilpy, Tolkunov, Denis, Aviv, Hana, Hakimi, Abraham A., Yao, Ming, Hsieh, James J., Ganesan, Shridar, Chan, Chang S., White, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779191/
https://www.ncbi.nlm.nih.gov/pubmed/26655904
http://dx.doi.org/10.1016/j.celrep.2015.10.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779191/
https://www.ncbi.nlm.nih.gov/pubmed/26655904
http://dx.doi.org/10.1016/j.celrep.2015.10.059

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