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A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

BACKGROUND: The understanding of changes in temporal processes related to human carcinogenesis is limited. One approach for prospective functional genomic studies is to compile trajectories of differential expression of genes, based on measurements from many case-control pairs. We propose a new stat...

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Detalles Bibliográficos
Autores principales: Lund, Eiliv, Holden, Lars, Bøvelstad, Hege, Plancade, Sandra, Mode, Nicolle, Günther, Clara-Cecilie, Nuel, Gregory, Thalabard, Jean-Christophe, Holden, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779232/
https://www.ncbi.nlm.nih.gov/pubmed/26944545
http://dx.doi.org/10.1186/s12874-016-0129-z