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An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials
BACKGROUND: Most in vitro studies investigating nanomaterial pulmonary toxicity poorly correlate to in vivo inhalation studies. Alveolar macrophages (AMs) play an outstanding role during inhalation exposure since they effectively clear the alveoli from particles. This study addresses the applicabili...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779246/ https://www.ncbi.nlm.nih.gov/pubmed/26944705 http://dx.doi.org/10.1186/s12951-016-0164-2 |