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An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

BACKGROUND: Most in vitro studies investigating nanomaterial pulmonary toxicity poorly correlate to in vivo inhalation studies. Alveolar macrophages (AMs) play an outstanding role during inhalation exposure since they effectively clear the alveoli from particles. This study addresses the applicabili...

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Detalles Bibliográficos
Autores principales: Wiemann, Martin, Vennemann, Antje, Sauer, Ursula G., Wiench, Karin, Ma-Hock, Lan, Landsiedel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779246/
https://www.ncbi.nlm.nih.gov/pubmed/26944705
http://dx.doi.org/10.1186/s12951-016-0164-2