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High expression of the human equilibrative nucleoside transporter 1 gene predicts a good response to decitabine in patients with myelodysplastic syndrome

BACKGROUND: Despite the efficacy of decitabine treatment in myelodysplastic syndrome (MDS), no definite predictor of response is known. In this study, we investigated whether the expression levels of human equilibrative nucleoside transporter 1 (hENT1), hENT2, deoxycytidine kinase (DCK) and cytidine...

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Detalles Bibliográficos
Autores principales: Wu, Lingyun, Shi, Wenhui, Li, Xiao, Chang, Chunkang, Xu, Feng, He, Qi, Wu, Dong, Su, Jiying, Zhou, Liyu, Song, Luxi, Xiao, Chao, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779250/
https://www.ncbi.nlm.nih.gov/pubmed/26944860
http://dx.doi.org/10.1186/s12967-016-0817-9