Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation

Cancer stem cells (CSCs) have tumor initiation, self-renewal, metastasis and chemo-resistance properties in various tumors including colorectal cancer. Targeting of CSCs may be essential to prevent relapse of tumors after chemotherapy. Phosphatidylinositol-3-kinase (PI3K) and mammalian target of rap...

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Detalles Bibliográficos
Autores principales: Kim, Min-Jung, Koo, Jeong-Eun, Han, Gi-Yeon, Kim, Buyun, Lee, Yoo-Sun, Ahn, Chiyoung, Kim, Chan-Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779859/
https://www.ncbi.nlm.nih.gov/pubmed/26955235
http://dx.doi.org/10.3346/jkms.2016.31.3.360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779859/
https://www.ncbi.nlm.nih.gov/pubmed/26955235
http://dx.doi.org/10.3346/jkms.2016.31.3.360

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