Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function

Insulin resistance, a critical component of type 2 diabetes (T2D), precedes and predicts T2D onset. T2D is also associated with mitochondrial dysfunction. To define the cause-effect relationship between insulin resistance and mitochondrial dysfunction, we compared mitochondrial metabolism in induced...

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Detalles Bibliográficos
Autores principales: Burkart, Alison M., Tan, Kelly, Warren, Laura, Iovino, Salvatore, Hughes, Katelyn J., Kahn, C. Ronald, Patti, Mary-Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780029/
https://www.ncbi.nlm.nih.gov/pubmed/26948272
http://dx.doi.org/10.1038/srep22788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780029/
https://www.ncbi.nlm.nih.gov/pubmed/26948272
http://dx.doi.org/10.1038/srep22788

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