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Influence of cyclosporine A on glomerular growth and the effect of mizoribine and losartan on cyclosporine nephrotoxicity in young rats

The aim of this study was to evaluate the influence of cyclosporine A (CsA) on glomerular growth and the effect of mizoribine (MZR) and losartan (LSAR) on CsA-induced nephropathy in young rats. Six-week-old male Sprague-Dawley rats maintained on a low salt diet were given CsA (15 mg/kg), CsA and LSR...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hong, Lee, Yeon Hee, Lim, Beom Jin, Jeong, Hyeon Joo, Kim, Pyung Kil, Shin, Jae Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780085/
https://www.ncbi.nlm.nih.gov/pubmed/26947764
http://dx.doi.org/10.1038/srep22374