Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer

Temozolomide-perillyl alcohol conjugate (TMZ − POH), a novel temozolomide analog, was reported to play a cytotoxic role in triple-negative breast cancer and TMZ-resistant gliomas. In a current study we had demonstrated how TMZ − POH also exhibited its cytotoxicity against non-small cell lung cancer...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Xingguo, Xie, Li, Wang, Xingwu, Zeng, Qian, Chen, Thomas C., Wang, Weijun, Song, Xianrang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780103/
https://www.ncbi.nlm.nih.gov/pubmed/26949038
http://dx.doi.org/10.1038/srep22762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780103/
https://www.ncbi.nlm.nih.gov/pubmed/26949038
http://dx.doi.org/10.1038/srep22762

Ejemplares similares