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Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer

Temozolomide-perillyl alcohol conjugate (TMZ − POH), a novel temozolomide analog, was reported to play a cytotoxic role in triple-negative breast cancer and TMZ-resistant gliomas. In a current study we had demonstrated how TMZ − POH also exhibited its cytotoxicity against non-small cell lung cancer...

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Detalles Bibliográficos
Autores principales:	Song, Xingguo, Xie, Li, Wang, Xingwu, Zeng, Qian, Chen, Thomas C., Wang, Weijun, Song, Xianrang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780103/ https://www.ncbi.nlm.nih.gov/pubmed/26949038 http://dx.doi.org/10.1038/srep22762

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