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pH regulation of amphotericin B channels activity in the bilayer lipid membrane
BACKGROUND: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects. The pH plays a crucial role in modulating biophysical features of ion channels in the bilayer lipid membranes. AIM: In this study, the role of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780175/ https://www.ncbi.nlm.nih.gov/pubmed/27003977 http://dx.doi.org/10.4103/0976-9668.175082 |