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Autophagy in Ischemic Livers: A Critical Role of Sirtuin 1/Mitofusin 2 Axis in Autophagy Induction

No-flow ischemia occurs during cardiac arrest, hemorrhagic shock, liver resection and transplantation. Recovery of blood flow and normal physiological pH, however, irreversibly injures the liver and other tissues. Although the liver has the powerful machinery for mitochondrial quality control, a pro...

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Detalles Bibliográficos
Autores principales: Chun, Sung Kook, Go, Kristina, Yang, Ming-Jim, Zendejas, Ivan, Behrns, Kevin E., Kim, Jae-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780240/
https://www.ncbi.nlm.nih.gov/pubmed/26977257
http://dx.doi.org/10.5487/TR.2016.32.1.035