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Mechanical insights into ribosomal progression overcoming RNA G-quadruplex from periodical translation suppression in cells
G-quadruplexes formed on DNA and RNA can be roadblocks to movement of polymerases and ribosome on template nucleotides. Although folding and unfolding processes of the G-quadruplexes are deliberately studied in vitro, how the mechanical and physical properties of the G-quadruplexes affect intracellu...
Autores principales: | Endoh, Tamaki, Sugimoto, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780275/ https://www.ncbi.nlm.nih.gov/pubmed/26948955 http://dx.doi.org/10.1038/srep22719 |
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