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Phenotypic Characteristics of PD-1 and CTLA-4 Expression in Symptomatic Acute Hepatitis A

BACKGROUND/AIMS: The immunoregulatory molecules programmed death 1 (PD-1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) are associated with the dysfunction of antiviral effector T-cells, which leads to T-cell exhaustion and persistent viral infection in patients with chronic hepatitis C a...

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Detalles Bibliográficos
Autores principales: Cho, Hyosun, Kang, Hyojeung, Kim, Chang Wook, Kim, Hee Yeon, Jang, Jeong Won, Yoon, Seung Kew, Lee, Chang Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780460/
https://www.ncbi.nlm.nih.gov/pubmed/26347518
http://dx.doi.org/10.5009/gnl14368