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Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells

BACKGROUND/AIMS: Statins act as antineoplastic agents through the inhibition of cell proliferation. This study sought to demonstrate the effects of statins on extrahepatic bile duct cancer cell apoptosis and to document the changes in protein expression involved in tumor growth and suppression. METH...

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Detalles Bibliográficos
Autores principales: Lee, Jin, Hong, Eun Mi, Jang, Ju Ah, Park, Se Woo, Koh, Dong Hee, Choi, Min Ho, Jang, Hyun Joo, Kae, Sea Hyub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780463/
https://www.ncbi.nlm.nih.gov/pubmed/26470769
http://dx.doi.org/10.5009/gnl15195