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A Parallel G Quadruplex-Binding Protein Regulates the Boundaries of DNA Elimination Events of Tetrahymena thermophila

Guanine (G)-rich DNA readily forms four-stranded quadruplexes in vitro, but evidence for their participation in genome regulation is limited. We have identified a quadruplex-binding protein, Lia3, that controls the boundaries of germline-limited, internal eliminated sequences (IESs) of Tetrahymena t...

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Detalles Bibliográficos
Autores principales: Carle, Christine M., Zaher, Hani S., Chalker, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780704/
https://www.ncbi.nlm.nih.gov/pubmed/26950070
http://dx.doi.org/10.1371/journal.pgen.1005842