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Joint Analysis of Multiple Traits Using "Optimal" Maximum Heritability Test

The joint analysis of multiple traits has recently become popular since it can increase statistical power to detect genetic variants and there is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Currently, most of existing methods use all of the traits for...

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Detalles Bibliográficos
Autores principales: Wang, Zhenchuan, Sha, Qiuying, Zhang, Shuanglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780705/
https://www.ncbi.nlm.nih.gov/pubmed/26950849
http://dx.doi.org/10.1371/journal.pone.0150975