A Method for Producing Protein Nanoparticles with Applications in Vaccines

A practical method is described for synthesizing conjugated protein nanoparticles using thioether (thiol-maleimide) cross-linking chemistry. This method fills the need for a reliable and reproducible synthesis of protein conjugate vaccines for preclinical studies, which can be adapted to produce com...

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Detalles Bibliográficos
Autores principales: Jones, David S., Rowe, Christopher G., Chen, Beth, Reiter, Karine, Rausch, Kelly M., Narum, David L., Wu, Yimin, Duffy, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780713/
https://www.ncbi.nlm.nih.gov/pubmed/26950441
http://dx.doi.org/10.1371/journal.pone.0138761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780713/
https://www.ncbi.nlm.nih.gov/pubmed/26950441
http://dx.doi.org/10.1371/journal.pone.0138761

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