Design of a novel theranostic nanomedicine: synthesis and physicochemical properties of a biocompatible polyphosphazene–platinum(II) conjugate

To develop a theranostic nanomedicine involving the antitumor-active moiety (dach)Pt(II) (dach: trans-(±)-1,2-diaminocyclohexane) of oxaliplatin (OX), a new biocompatible polyphosphazene carrier polymer was designed by grafting with a methoxy poly(ethylene glycol) (MPEG) to increase duration of circ...

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Detalles Bibliográficos
Autores principales: Avaji, Prakash G, Park, Jung Hyun, Lee, Hyun Jeong, Jun, Yong Joo, Park, Kyung Su, Lee, Kyung Eun, Choi, Soo-Jin, Lee, Hwa Jeong, Sohn, Youn Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780734/
https://www.ncbi.nlm.nih.gov/pubmed/27042052
http://dx.doi.org/10.2147/IJN.S99917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780734/
https://www.ncbi.nlm.nih.gov/pubmed/27042052
http://dx.doi.org/10.2147/IJN.S99917

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