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Loss of CD28 on Peripheral T Cells Decreases the Risk for Early Acute Rejection after Kidney Transplantation

BACKGROUND: End-stage renal disease patients have a dysfunctional, prematurely aged peripheral T-cell system. Here we hypothesized that the degree of premature T-cell ageing before kidney transplantation predicts the risk for early acute allograft rejection (EAR). METHODS: 222 living donor kidney tr...

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Detalles Bibliográficos
Autores principales: Dedeoglu, Burç, Meijers, Ruud W. J., Klepper, Mariska, Hesselink, Dennis A., Baan, Carla C., Litjens, Nicolle H. R., Betjes, Michiel G. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780739/
https://www.ncbi.nlm.nih.gov/pubmed/26950734
http://dx.doi.org/10.1371/journal.pone.0150826