Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice

During the analysis of a whole genome ENU mutagenesis screen for thrombosis modifiers, a spontaneous 8 base pair (bp) deletion causing a frameshift in exon 27 of the Nbeal2 gene was identified. Though initially considered as a plausible thrombosis modifier, this Nbeal2 mutation failed to suppress th...

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Detalles Bibliográficos
Autores principales: Tomberg, Kärt, Khoriaty, Rami, Westrick, Randal J., Fairfield, Heather E., Reinholdt, Laura G., Brodsky, Gary L., Davizon-Castillo, Pavel, Ginsburg, David, Di Paola, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780761/
https://www.ncbi.nlm.nih.gov/pubmed/26950939
http://dx.doi.org/10.1371/journal.pone.0150852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780761/
https://www.ncbi.nlm.nih.gov/pubmed/26950939
http://dx.doi.org/10.1371/journal.pone.0150852

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