Indexed PCR Primers Induce Template-Specific Bias in Large-Scale DNA Sequencing Studies

Massively parallel sequencing is rapidly emerging as an efficient way to quantify biodiversity at all levels, from genetic variation and expression to ecological community assemblage. However, the number of reads produced per sequencing run far exceeds the number required per sample for many applica...

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Detalles Bibliográficos
Autores principales: O’Donnell, James L., Kelly, Ryan P., Lowell, Natalie C., Port, Jesse A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780811/
https://www.ncbi.nlm.nih.gov/pubmed/26950069
http://dx.doi.org/10.1371/journal.pone.0148698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780811/
https://www.ncbi.nlm.nih.gov/pubmed/26950069
http://dx.doi.org/10.1371/journal.pone.0148698

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