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Indexed PCR Primers Induce Template-Specific Bias in Large-Scale DNA Sequencing Studies
Massively parallel sequencing is rapidly emerging as an efficient way to quantify biodiversity at all levels, from genetic variation and expression to ecological community assemblage. However, the number of reads produced per sequencing run far exceeds the number required per sample for many applica...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780811/ https://www.ncbi.nlm.nih.gov/pubmed/26950069 http://dx.doi.org/10.1371/journal.pone.0148698 |