Cargando…

Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice

Pravastatin is a lipid-lowering agent that attenuates atherosclerosis. However, the multifactorial pathogenesis of atherosclerosis requires other drugs with different anti-atherogenic mechanisms. We chose sarpogrelate as an anti-platelet agent and a novel component of a complex drug with pravastatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Kyung-Yeon, Oh, Euichaul, Kwak, Mi-Kyoung, Jun, Hyun Sik, Heo, Tae-Hwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780828/
https://www.ncbi.nlm.nih.gov/pubmed/26950217
http://dx.doi.org/10.1371/journal.pone.0150791