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Family-wide Structural Analysis of Human Numb-Associated Protein Kinases

The highly diverse Numb-associated kinase (NAK) family has been linked to broad cellular functions including receptor-mediated endocytosis, Notch pathway modulation, osteoblast differentiation, and dendrite morphogenesis. Consequently, NAK kinases play a key role in a diverse range of diseases from...

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Detalles Bibliográficos
Autores principales: Sorrell, Fiona J., Szklarz, Marta, Abdul Azeez, Kamal R., Elkins, Jon M., Knapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780864/
https://www.ncbi.nlm.nih.gov/pubmed/26853940
http://dx.doi.org/10.1016/j.str.2015.12.015