Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

Genome-editing of human pluripotent stem cells (hPSCs) provides a genetically controlled and clinically relevant platform from which to understand human development and investigate the pathophysiology of disease. By employing site-specific nucleases (SSNs) for genome editing, the rapid derivation of...

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Detalles Bibliográficos
Autores principales: Blair, John D., Bateup, Helen S., Hockemeyer, Dirk F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2016
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781717/
https://www.ncbi.nlm.nih.gov/pubmed/26863600
http://dx.doi.org/10.3791/53583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781717/
https://www.ncbi.nlm.nih.gov/pubmed/26863600
http://dx.doi.org/10.3791/53583

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