In-silico screening of Schistosoma mansoni Sirtuin1 inhibitors for prioritization of drug candidates

Schistosomiasis is a common, neglected parasitic disease caused by Schistosoma mansoni. Availability of two specific drug oxamniquine and praziquintel for treatment of the disease is a major concern. Recently NAD+ dependent lysine deacetylases have been identified as new drug targets in pathogens. S...

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Detalles Bibliográficos
Autores principales: Singh, Raghvendra, Yadav, Birendra Singh, Singh, Swati, Pandey, Paras Nath, Mani, Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781818/
https://www.ncbi.nlm.nih.gov/pubmed/27066323
http://dx.doi.org/10.1186/s40064-016-1891-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781818/
https://www.ncbi.nlm.nih.gov/pubmed/27066323
http://dx.doi.org/10.1186/s40064-016-1891-4

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