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Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review
Essential proteins/genes are indispensable to the survival or reproduction of an organism, and the deletion of such essential proteins will result in lethality or infertility. The identification of essential genes is very important not only for understanding the minimal requirements for survival of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781880/ https://www.ncbi.nlm.nih.gov/pubmed/27014079 http://dx.doi.org/10.3389/fphys.2016.00075 |