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Mechanisms of metabolic dysfunction in cancer-associated cachexia

Metabolic dysfunction contributes to the clinical deterioration observed in advanced cancer patients and is characterized by weight loss, skeletal muscle wasting, and atrophy of the adipose tissue. This systemic syndrome, termed cancer-associated cachexia (CAC), is a major cause of morbidity and mor...

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Detalles Bibliográficos
Autores principales: Petruzzelli, Michele, Wagner, Erwin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782044/
https://www.ncbi.nlm.nih.gov/pubmed/26944676
http://dx.doi.org/10.1101/gad.276733.115